Free Form vs Peptide Bonded
Much of the ingested free form
l-glutamine does not make it into the blood stream or muscle tissue. It is estimated that anywhere from 50-85% is immediately used by the intestines, liver, and the immune system. This is what many scientists refer to as the “glutamine paradox": a problem which is apparently solved by using the
glutamine peptide bonded chain.
glutamine peptide is also much more stable in solution, higher temperatures, and low PH than free form
l-glutamine since it tends to break down to ammonia and glutamic acid rather quickly in solution. The digestive tract has peptide transport systems that allow peptides to be better absorbed and utilized. Therefore, the peptide bonded form is thought to enhance the availability of the
glutamine in the bloodstream, making it more readily available to muscle tissue.
glutamine peptides are bonded to other amino acids with peptide bonds, making them more stable and better utilized by the body. A product that combines both ensures better uptake, absorption, and stability and allows for better transport into the blood stream and muscle tissue.
It is acknowledged, however, that both forms help protect against the side effects of cancer treatments. Hospital stays have been reduced by those who have undergone major abdominal surgeries and were given
glutamine supplements. Since the immune system relies heavily on
glutamine, overall immune function appears to be better in hospital patients as evidenced by increased lymphocyte counts and the generation of neutrophils. Therefore, it may be a wise addition for everyone prone to many health problems.