Why we should all use Exemestane

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  1. #1
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    Why we should all use Exemestane

    Heres an article I found on another website guys.


    Aromasin (exemestane) is a steroid-al AI - an irreversible aromatase inhibitor ... great for controlling estrogen "during cycle" and "PCT" ...

    But, what else does it do ???
    Good reading....

    ABSTRACT FROM JOURNAL OF CLINICAL ENDOCRONOLOGY AND METABOLISM

    Suppression of estrogen, via estrogen receptor or aromatase blockade, is being investigated in the treatment of different conditions. Exemestane (Aromasin) is a potent and selective irreversible aromatase inhibitor. To characterize its suppression of estrogen and its pharmacokinetic (PK) properties in males, healthy eugonadal subjects were recruited. In a cross-over study, 12 were randomly assigned to 25 and 50 mg exemestane daily, orally, for 10 d with a 14-d washout period. Blood was withdrawn before and 24 h after the last dose of each treatment period. A PK study was performed (n = 10) using a 25-mg dose.

    RESULTS :

    The 25- and 50-mg doses of daily exemestane had comparable effects in suppressing circulating estrogen concentrations, with 38 ± 24% (mean ± SD; P = 0.002 vs. baseline) and 32 ± 29% (P = 0.008) decreases in estradiol concentrations, 71 ± 12% (P < 0.0001) and 74 ± 12% (P < 0.0001) decreases in estrone concentrations, and 45 ± 27% (P = 0.004) and 51 ± 20% (P = 0.02)

    BUT THERE'S MORE

    There was an increase in circulating testosterone concentrations after both 25 mg (60 ± 58%; P = 0.001) and 50 mg (56 ± 48%; P = 0.003) exemestane. Androstenedione concentrations were increased as well after 25 mg (32 ± 36%; P = 0.004) and 50 mg (47 ± 59%; P = 0.052) exemestane, respectively (Fig. 1Go and Table 2Go).

    SHBG concentrations were decreased by 21 ± 7% (P = 0.0003) and 19 ± 39% (P = 0.18) at 25 and 50 mg exemestane, respectively.

    Free testosterone concentrations were increased by 117 ± 74% (P = 0.0001) and 154 ± 95% (P < 0.0001) at both doses, due to the decrease in SHBG and the increase in total testosterone.

    THE ICING ON THE CAKE !

    There were no changes in circulating serum triglycerides, cholesterol, or LDL or HDL cholesterol concentrations with either dose of exemestane.

  2. #2
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    I've always used arimidex. Is aromasin really better?

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    Good post, have always gone with aromasin over adex - better overall, less chance of rebound, less sides, obvious choice overall IMO

  4. #4
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    http://www.TrannyUrine.com/
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    Quote Originally Posted by SFW View Post
    Looks like you need a cup of

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    I prefer aromasin.

  7. #7
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    Quote Originally Posted by tballz View Post
    I prefer aromasin.
    exemestane = aromasin

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    fo shizzle

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    Quote Originally Posted by ScottyMac710 View Post
    exemestane = aromasin
    Yea...I know.

  10. #10
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    Adex on and aromasin after.
    Anything I post on this board is based on Fantasy and Science Fiction...and stuff I may or may not have read somewhere else...

  11. #11
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    I used aromasin this time around (with clomid) I will never use anything else. I feel like I recovered so perfectly, it definitely did its job

  12. #12
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    i like this stuff it's very good

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    good info

  14. #14
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    awesome, makes me glad i just ordered some!

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    Appreciate the info.

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