Been using the Melantonin and Withania, haven?t noticed anything yet, give it time i suppose. We have had really bad weather where i live, i had to move some pot plants in pots the other day, probably weighed no more than 25 pounds each. Well i got real sore through the guts, upper abdominal, shoulder blades, its hard to imagine this is now the norm. Last time i got real sore in between the shoulder blades was from seated rows with good form, slow and heavy. Need to address this. I have another approach to try soon.