Follow Us on Facebook        Subscribe to us on YouTube        Follow Us on Twitter        IronMagLabs on Instagram        Sign Up for our Newsletter


Leucine and Muscle Growth

Results 1 to 4 of 4
  1. #1
    Registered User


    Join Date
    May 2008
    Location
    Rio Rancho, NM
    Posts
    754
    Rep Points
    44182007

    Leucine and Muscle Growth






    Leucine and Muscle Growth
    Leucine and Muscle Growth


    This is another good article by Mike Arnold.

    However, there appears to be an underlying factor in how well Leucine elicits the mTOR "Growth Factor Effect."

    How to Harness the Anabolic Power of Cell Volume
    Bill Willis

    ...it takes more than just leucine to activate mTOR ? glutamine is also required

    Glutamine was necessary for leucine uptake and cell volumization, both of which are needed to turn on protein synthesis. ...cellular glutamine depletion not only results in a reduction of cell volume, but also reduces the ability of leucine to activate protein synthesis.

    glutamine is necessary for the activation of protein synthesis by leucine.

    Takeaways from this study:

    ?Glutamine is needed for leucine to gain access into the cell to turn on protein synthesis.

    ?Glutamine induced cell volumization is necessary to turn on mTOR and protein synthesis

    glutamine export is coupled to leucine import and mTOR activation.

    To get leucine into the cell, there's an initial period of "glutamine loading."

    Takeaways from this study:

    ?Glutamine is rate limiting for leucine activation of protein synthesis.

    ?A cell must be "glutamine pre-loaded" to import leucine.

    Personal Observation

    In spiking my whey protein beverage with Leucine, I didn't see much difference.

    I suspect (I am guessing) that I was already consuming enough Leucine.

    Thus, adding more didn't do anything for me.

    Eventually a blind pick will run into an apple.

    Inadvertently, I decided add Glutamine to my mix for a different reason.

    In doing so, I obtain a much better training effect...my training sessions improved.

    I suspect (guessing again) that I was deficient in Glutamine.

    Thus, adding Glutamine to the mix provided a...

    Synergistic Effect

    Synergistic amounts to 2 + 2 = 5...the sum being greater than it's individual parts.

    Bottom Line

    Based on the research, it appears that Leucine's effect is enhanced with Glutamine.

    Kenny Croxdale

  2. #2
    SF Associate
    BOARD REP
    tsek0s's Avatar


    Join Date
    Oct 2013
    Gender
    Male
    Location
    steroidsfax.com
    Posts
    212
    Rep Points
    5829226

    Great infos bro!!

  3. #3
    Senior Member
    ELITE MEMBER
    Christsean's Avatar


    Join Date
    Jul 2013
    Gender
    Male
    Location
    Texas
    Posts
    1,781
    Rep Points
    183383697

    Kenny thanks for chewing it up and feeding it to us. I've always enjoyed thee benefits if adding 5 grams of glutamine to my PWO shake. Maybe placebo but it works for me.

  4. #4
    Registered User


    Join Date
    Dec 2013
    Gender
    Male
    Location
    USA
    Posts
    37
    Rep Points
    10






    glutamine has been shown to be awesome for gut health.

Similar Threads

  1. Leucine and Muscle Growth
    By Prince in forum Articles
    Replies: 0
    Last Post: 12-06-2013, 11:50 AM
  2. Twelve grams a day of leucine boosts muscle mass
    By Prince in forum Supplements
    Replies: 1
    Last Post: 04-04-2012, 03:11 PM
  3. Replies: 0
    Last Post: 11-21-2011, 09:50 AM
  4. Replies: 0
    Last Post: 06-27-2011, 01:57 PM
  5. Amino Acid Leucine No Aid to Muscle Recovery
    By Prince in forum Bodybuilding Gossip
    Replies: 0
    Last Post: 09-01-2010, 11:40 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
DISABLED END -->