What Is Cialis (Tadalafil)
Cialis is a brand name for a substance with the chemical name tadalafil. It is used to treat men who experience difficulty having and maintaining an erection to orgasm.
It was first introduced in February 2003 and it was approved by the FDA on November 21, 2003. Cialis was first marketed by Lilly ICOS, a joint venture between Eli Lilly and ICOS Corporation.
The standard starting dose size is 10 milligrams. In some cases a 20 milligram dose is necessary. Cialis should be taken orally 30 minutes or longer before sexual activity.
Medical testing has shown that cialis is effective in 60%-80%, of cases when used to treat erectile dysfunction in men. Most failure cases are from men that have had some form of surgery that made getting or maintaining an erection physically impossible. During PCT a man may find it more difficult to have or maintain an erection so Cialis is a possible solution to that problem.
Cialis produces results similar to viagra, but the effects of cialis last longer than viagra. In addition, cialis can be taken on an empty stomach or with a meal. When Cialis and Viagra were compared in a study Cialis allowed for more sexual frequency and that in turn raised Testosterone levels higher in the Cialis group.
Viagra should not be taken with high fat foods because these foods reduce absorption of viagra in the human body. Cialis on the other hand may be used even when dining on high fat foods, with no decrease in effects.
How Does Cialis Work
Medications like cialis, viagra, and levitra work by inhibiting a chemical called phosphodiesterase type 5. Because of their mode of action, these drugs are commonly referred to simply as PDE5 inhibitors.
When a man gets sexually excited, it triggers cells in the penis to produce nitric oxide. The increase in nitric oxide will in turn cause production of cyclic guanosine monophosphate (cGMP). The cGMP causes arteries in part of the penis to relax and allow more blood to flow through them. The increase in blood flow causes an erection.
If the enzyme phosphodiesterase type 5 (PDE5) is of sufficient quantity, it will attack the cGMP and erection will not be maintained. Cialis and other PDE5 inhibitors reduce the amount of PDE5 available to attack cGMP. With a reduction of PDE5, most men are able to maintain an erection to orgasm.
How Long Do the Effects of Cialis Last
The effects of cialis have been shown to last 24 to 36 hours in a majority of users. The effects of viagra have been shown to last 4 to 6 hours in a majority of users.
Some men like the fact that cialis works for up to 36 hours and allows the user and his partner to relax, forget about planning intimacy and let things happen when the moment is right.
24 to 36 hours might seem ideal but some men report they switched back to viagra because 6 hours or less was what they preferred. I have personally have had good results from Cialis anywhere from 1-36 hours after taking it but 24 hours seems to be a peak time for me.
Taking cialis does not increase sexual desire directly and it will not give you an erection for 36 hours. Most men who take cialis report that for up to 36 hours after taking cialis, an erection can be sustained when the penis was stimulated by touch. After orgasm, the penis will usually return to its pre-aroused state.
Some men may be able to have one or more orgasms after the first but this an exception. In most cases, within 36 hours of taking 20 milligrams of cialis, you will be able to get and maintain an erection to orgasm one time.
Most men that have had more than one orgasm from a single dose say they had the first orgasm within 60-180 minutes of taking cialis then were able to have one or more orgasms by waiting 60 minutes or longer before any more penis stimulation was attempted. This is something the user will have to experiment with to find out their own particular climax capacity.