IronMag Research

25% Off Black Friday Sale

Advantages and disadvantages of GH/IGF-I combination treatment

Results 1 to 5 of 5
  1. #1
    Capt'n Finaplix
    BOARD REP
    basskiller's Avatar


    Join Date
    Sep 2002
    Gender
    Male
    Location
    From the Deep Dark Bowels of a Land called FINA! The place where only the Strongest Craziest Muther Fuckers Dare to Go!
    Posts
    429
    Rep Points
    103533259

    Advantages and disadvantages of GH/IGF-I combination treatment

    Advantages and disadvantages of GH/IGF-I combination treatment
    Growth hormone (GH) is the primary regulator of insulin-like growth factor-I (IGF-I) production in a wide variety of tissues. There is much overlap in the endocrine, metabolic and anabolic effects of GH and IGF-I but both hormones have divergent effects on glucose metabolism, insulin sensitivity and differentiation of prechondrocytes.
    Theoretically combined administration of GH and IGF-I may be more effective than GH alone or IGF-I alone.

    Arguments in favor for this are:
    1) Clearance of IGF-I may be markedly altered by the co-administration of GH and this will provide sustained actions of IGF-I.
    2) Higher serum IGF-I levels are achieved with a combination treatment of GH and IGF-I than with GH treatment alone or IGF-I alone. In addition, combination therapy may have additive or synergistic effects.
    3) The combination GH and IGF-I counteracts disadvantageous effects on glucose metabolism of either GH alone or IGF-I alone.
    4) GH may exert direct actions on tissues independently from IGF-I.
    5) Combination of GH and IGF-I may be more effective in improving tissue IGF-I levels. The combination therapy of GH and IGF-I might be beneficial in growth retardation, in certain specific subgroups of critically ill or catabolic patients and in the treatment of GH-deficient subjects with the metabolic syndrome and/or manifest diabetes.

    It is at present unknown whether an optimal balance between safety and efficacy can be achieved with the combination therapy of GH and IGF-I, since this combination has been evaluated in only a small number of patient populations and in studies of a relatively short duration.
    In addition, a disadvantage may be the financial costs of combination therapy of GH and IGF-I.

    In conclusion, there are many reasons for believing that administration of the combination therapy of GH and IGF-I could have advantages above GH alone or IGF-I alone. However, determination of whether co-administration of GH and IGF-I indeed is superior to either agent alone awaits further study.

    J. A. M. J. L. Janssen
    pm me for questions

  2. #2
    Member
    BOARD REP
    psychowhite's Avatar


    Join Date
    Apr 2014
    Gender
    Male
    Location
    USA
    Posts
    223
    Rep Points
    20804248

    Thanks for posting this bk!

    www.levram.us

  3. #3
    senior memeber


    Join Date
    Apr 2011
    Gender
    Male
    Location
    working out
    Posts
    1,716
    Rep Points
    62344335

    i have ran both at the same time and i got crazy results.i like to run hgh, igf and peptides so that i can run lower doses of all and get great results at a cheaper price.

  4. #4
    Registered User


    Join Date
    Jul 2014
    Gender
    Male
    Location
    waterboro,maine 04030
    Posts
    245
    Rep Points
    774015

    Quote Originally Posted by BIGBEN2011 View Post
    i have ran both at the same time and i got crazy results.i like to run hgh, igf and peptides so that i can run lower doses of all and get great results at a cheaper price.
    Ya,this is what I am thinking,IGF-1 and GHRP-2 or 6 and see what it lends for results,also cut back on my gear and add this.

  5. #5
    Senior Member
    BOARD REP
    Dannie's Avatar


    Join Date
    Jul 2011
    Gender
    Male
    Location
    Denmark
    Posts
    1,799
    Rep Points
    85023022

    Good read thanks for posting.
    The AA is a in the post, currently saving up for a couple of more vials of IGF1 LR3.

Similar Threads

  1. What are the advantages of a business account?
    By HialeahChico305 in forum Open Chat
    Replies: 4
    Last Post: 04-07-2011, 04:41 PM
  2. advantages of winstrol
    By premo in forum Anabolic Zone
    Replies: 32
    Last Post: 07-14-2010, 04:25 PM
  3. What would be the advantages of inject creatine
    By Supermans Daddy in forum Anabolic Zone
    Replies: 16
    Last Post: 04-29-2010, 09:31 PM
  4. advantages and disadvantages of running deca?
    By Tha Don in forum Anabolic Zone
    Replies: 11
    Last Post: 09-17-2005, 04:03 PM
  5. Advantages/Disadvantages to whole body W/O's
    By SKINSFAN in forum Training
    Replies: 2
    Last Post: 01-26-2002, 03:33 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
-->