Animal study: AHCC restrains the causative agent of pneumonia
In the worst case scenario of an infection with the coronavirus, the immune system collapses and bacteria such as Klebsiella pneumoniae take their chance. They colonize the lungs and can reach the bloodstream from there. According to an animal study published by biologists from State University of New York at Binghamton in 2007, supplementation with AHCC may help prevent this potentially fatal situation.Study
The researchers injected mice with a dose of Klebsiella pneumoniae that should kill half of the test animals [LD50].

Klebsiella pneumoniae is a bacteria that lives on and in the human body. If the immune system collapses - under pressure from an aggressive virus, for example - Klebsiella pneumoniae can develop into a dangerous and potentially deadly germ.

Half of the mice received a dose of AHCC every day 8 days before the injection. The supplementation continued after the injection.The dose the researchers used was high. If the mice had been human, they would have received 6-8 grams of AHCC per day. The dose the researchers used was the highest effective dose they could find in previously published animal studies.
The study was funded by the Japanese Amino Up, [] the producer of AHCC.

The mice receiving AHCC survived Klebsiella pneumoniae infection more often than the mice in the control group.

Fifteen days after injecting their mice with the bacteria, the researchers looked to see if they could find the bacteria in the surviving mice. The percentage of mice in which this was the case was significantly lower in the AHCC group. AHCC apparently stimulates the immune system to clean up bacteria.

"This finding suggests that AHCC may be useful in helping to clear bacteria in patients with trauma or undergoing surgical procedures", the researchers write.

We suspect that AHCC and similar preparations may have even more useful applications. But we don't have to explain that.
Surg Infect (Larchmt). 2006;7(6):527-35.