Future Cure for Diabetes?

Results 1 to 2 of 2
  1. #1
    DOMS's Avatar

    Join Date
    Jul 2004
    In a van, down by the river...

    Thanks Thanks Given 
    Thanks Thanks Received 
    Thanked in
    1 Post
    Rep Points

    Future Cure for Diabetes?

    Read here.

    "A Japanese woman has been cured of diabetes via a donor transplant of insulin-producing cells from her mother."

    However (for now):

    "However, the woman must take powerful drugs to stop her rejecting the new cells, according to Matsumoto."

  2. #2
    inadvertant tree hugger
    bandaidwoman's Avatar

    Join Date
    Dec 2003
    Atlanta, Georgia

    Thanks Thanks Given 
    Thanks Thanks Received 
    Thanked in
    0 Posts
    Rep Points

    It is called islet cell transplantation:

    The success rate for islets surviving for more than 1 year with an insulin-free patient was pretty dismal until this last year when the Alberta (Canada) experience was reported. The efforts of this group improved considerably on earlier results.

    However, problems remain, especially with the availability of donor islets for transplantation. The number of islets injected for this procedure usually required 2 donors per patient. Also, of the patients reported in the Alberta study, at least half of them required a second transplant and some a third. Thus, 4 donors are often required for these patients, far more than for the whole organ transplant. There are currently only about 5000 human pancreases that become available in the United States for transplantation each year. Only 2500 are thought to be viable for islet isolation, thus only about 5-700 people will benefit. So, this girl may be in for 2-3more transplants. and with the above information, large scale implementation for all those type I juvenile diabetes is dismal.

    However, stem cell research may solve this problem in two ways:

    Intersting these islet cells are not "terminal cells" but undergo replacement at the rate of about 2%/month.

    The new islets can derive from existing islets, a process known as replication, or from protodifferentiated stem cells, referred to as islet neogenesis.

    The objective is to identify islet stem cells and expand islet numbers through in vitro (in test tubes or culture plates ) cultivation before transplantation.

    Several investigators, both in the United States and in Europe, are working with fetal islet cell clusters as the ideal starting material for islet expansion. These are the supposed stem cells in the normal fetal development of islets. The thinking is that if these clusters can be kept in an environment that promotes development and differentiation, perhaps they can be induced to produce islets indefinitely in a culture!

    A second approach is to identify the stem cell population in the adult pancreas and culture them in appropriate conditions to induce expansion in number and development into viable islets.

    This would represent a step forward in making sufficient islet numbers available to treat a significant portion of the diabetes patient population.
    Official Race Member of the Crank Crushing Rednecks

    Eat more mud, mountain bike until you die!

    XX Feminine power

Similar Threads

  1. Anti-diabetes drugs may cause diabetes
    By Prince in forum General Health & Awareness
    Replies: 2
    Last Post: 03-31-2012, 02:18 AM
  2. Potential ?Cure? for Type 1 Diabetes?
    By Prince in forum Muscle Central
    Replies: 0
    Last Post: 06-27-2011, 12:57 PM
  3. Potential ?Cure? for Type 1 Diabetes?
    By Prince in forum Muscle Central
    Replies: 1
    Last Post: 02-04-2011, 09:47 PM
  4. Cure For Hypertension..Common Sense Cure...Farts
    By Hoglander in forum General Health & Awareness
    Replies: 4
    Last Post: 10-26-2008, 02:37 AM
  5. Study: Obesity surgery can cure diabetes (AP)
    By RSS Feed Robot in forum General Health & Awareness
    Replies: 0
    Last Post: 01-22-2008, 11:50 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
Copyright© 2001-2018 IronMag® Bodybuilding Forums