I know most of all supplements have different affects on different people. For me I was lifting about 6 days a week normally and taking around 2 scoops of no-xplode every time before I worked out and I was also using the BSN nitrix pills. One day I completely stopped taking the no-xplode and a few days later I stopped taking the nitrix. I have been very depressed and I havent felt like doing anything since I stopped taking it and I havent wanted to lift weights either. No-xplode had the same effects on my friend also. Has anyone else experienced this?