Ive used many brands of protein powders from some of th cheapest brands to the most expensive brands when I first began weight training.
I soon realized things werent are dry and cut as they first seemed and that the protein I was consuming could be dangerous and alot of the time was dangerous so now I only use one make of protein powder.
Lets begin with one of the most popular protein powder around Muscle milk Plz take the time and carefully read this article on this link.
The only thing is, I have the Muscle Milk WHEY protein (not the one that is shown in the picture that he is talking about...the one with the huge amounts of fat in it) and the ingredients list none of the things he is talking about. Is he refering to just that one product?
Ive drank it for quite some time and though I am not a "gung-ho" customer, I would just have to hear both sides of the story. I am not a biochemist, doctor, or scientist, so I cant really believe everything I read without hearing everything.
Interesting study though. I dont drink as much muscle milk as I used to, I usually split it with another product since muscle milk isnt that expensive.
That article, I dont know, it reminds me of some coverage I saw on 60minutes or Dateline NBC about microwaves causing cancer and cell phones causing tumors. They have valid points, but to live in fear about shit like that is insane. I know a friends mom that wanted to remove her microwave from her house cuz it was going to kill her. Yeah, I want to be like that.
This compound is NOT likely to build up to cytotoxic levels because you have methionine transmethylation reactions that results in natural creatine synthesis.
Only GAMT gene deficient individuals would have neurotoxic effects from using this compound.
But wait, our author presupposes that because you aren't getting your full fucking 10 grams of betaine anhydrous, your aren't getting your fill of methylation power.
He then *misses* the only salient ingredient that you might want to think twice about in this product: CLA.
Its a mixture of isomers, one is exaggerates and other controls insulin response. Most of us do no recommend its use. The company really should reconsider its use, along with the dose of MCT (which this author correctly points to being on the high side).
Creatine is formed by the transmethylation of guanidine-acetic acid ransmethylation with methionine. The methionine is the endproduct of the folate/homocysteine pathway in liver.
The rest of the story:
Activation of GABA(A) receptors by guanidinoacetate: a novel pathophysiological mechanism. Neu A, Neuhoff H, Trube G, Fehr S, Ullrich K, Roeper J, Isbrandt D. Zentrum fur Molekulare Neurobiologie Hamburg, Universitat Hamburg, Germany. Neurobiol Dis. 2002 11(2):298-307.
Guanidinoacetate methyltransferase (GAMT) deficiency is an autosomal recessively inherited disorder of creatine biosynthesis. The disease occurs in early life with developmental delay or arrest and several neurological symptoms, e.g., seizures and dyskinesia. Both the deficiency of high-energy phosphates in neurons and the neurotoxic action of the accumulated metabolite guanidinoacetate (GAA) are candidate mechanisms for the pathophysiology of this disease. To examine a potential role of GAA accumulation, we analyzed the electrophysiological responses of neurons induced by GAA application in primary culture and acute murine brain slices. GAA evoked picrotoxin- and bicuculline-sensitive GABA(A) receptor-mediated chloride currents with an EC(50) of 167 microM in cortical neurons. Pathophysiologically relevant GAA concentrations hyperpolarized globus pallidus neurons and reduced their spontaneous spike frequency with an EC(50) of 15.1 microM. Furthermore, GAA acted as a partial agonist at heterologously expressed GABA(A) but not GABA(B) receptors. The interaction of GAA with neuronal GABA(A) receptors represents a candidate mechanism explaining neurological dysfunction in GAMT deficiency.
The guy who wrote that article isn't the same one who said that Swole V2 and NO-Xplode were bad for your health too?
I'll say this being 100% honest. I thing that I like about ironmagazineforums.com is that we don't see biased threads like that.
We all know about Muscletech issue, but I've never seen Mr DiMaggio write a whole thread to diss a product.
IMO this guy just trying to create controversy.
Seriously, with all the safety measure in the U.S. post 9/11, do you honestly think the FDA or USDA will allow companies to sell something that could potentially harm you?
What happened with ephedra? They said it was bad for you and they banned it. What happened with Pro Hormones (eventhough I didn't agree on this one) they thought they were bad and banned!
So do you think that if a product is dangerous enough to posses a threat to your health the U.S. Govermentment won't do something to take off the market?