Start with 40 mcg/day first thing in the morning. Increase your dose 20 mcg/day until you feel you have reached your maximum dose, which is usually around 120 mcg/day. Do not exceed 160 mcg/day. Continue to use that max daily dose until you have completed a cycle of 2-3 weeks. Then take 2 weeks off from clen. Taking 50 mg of Benedryl a day during the course of your cycle will help keep your receptors unregulated, which allows the clen to continue to work well after the two week mark. Never use a dose higher than is comfortable for you and always drink plenty of water.