That sounds interesting, but it does go against other principles out there. Namely, I read about one in a book by Zatsiorsky which he based on the notion of contractile protein degradation. Basically, the greater the intensity (As in percentage of your 1RM), the greater the level of contractile protein degradation. The greater the number of reps, the greater the level of contractile protein degradation. The greater the level of degradation, the greater the level of super-compensation. He determined that the range that optimizes this protein degradation is 4-12 repetitions (I believe; it may have been 5-12).
However, this doesn't mean Little's theory is incorrect. I'm merely presenting an alternative theory from the think tank of a respected physiologist. It's all hypothesis and theory. I believe it's worth trying at some point.



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