Sip it immediately pre-workout (during workout is best) you want to do it on an empty stomach free of whole proteins. It's mechanism of action is that it passes digestion in the stomach and is rapidly assimilated. So if you add whole proteins it's going to defeat the purpose, and take a while to be absorbed. I'd recommend looking into BCAA's if you do a lot of high intensity cardio, weight lifting, or a restricted Calorie diet and you want to preserve lean body mass. I'd take 5-10g. per dose.