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raloxifene vs tamoxifen
raloxifene vs tamoxifen
Objectives: To assess the efficacy of the anti-estrogens tamoxifen and raloxifen in the medical management of persistent pubertal gynecomastia.
Study design: Retrospective chart review of 38 consecutive patients with persistent pubertal gynecomastia who presented to a pediatric endocrinology clinic. Patients received reassurance alone or a 3- to 9-month course of an estrogen receptor modifier (tamoxifen or raloxifene).
Results: Mean (SD) age of treated subjects was 14.6 (1.5) years with gynecomastia duration of 28.3 (16.4) months. Mean reduction in breast nodule diameter was 2.1 cm (95% CI 1.7, 2.7, P <.0001) after treatment with tamoxifen and 2.5 cm (95% CI 1.7, 3.3, P <.0001) with raloxifene. Some improvement was seen in 86% of patients receiving tamoxifen and in 91% receiving raloxifene, but a greater proportion had a significant decrease (>50%) with raloxifene (86%) than tamoxifen (41%). No side effects were seen in any patients.
Conclusion: Inhibition of estrogen receptor action in the breast appears to be safe and effective in reducing persistent pubertal gynecomastia, with a better response to raloxifene than to tamoxifen. Further study is required to determine that this is truly a treatment effect.
Like in the above study both tamoxifen and raloxifene works and reducing and shrinking all ready existing gyno but one does it better and has better effect overall as tamoxifen is known at lowering igf1 levels and other issues with prolactin side effects that raloxifene doesn’t do
The next thing that can help improve appearance of the nipple gland anvar or winstrol they have a anti prolactin lowering effect which can then give better appearance to the gland
Masteron I can say also has this effect as with it being a dht and giving a drying effect your nipples will also appear more stiff tighter less puffy
Conclusion here for the aesthetics of the nipples
raloxifene 60mg daily
winstrol or anavar 50mg daily
Masteron 400-600mg weekly
Sent from my SM-G998U using Tapatalk
raloxifene vs tamoxifen
Objectives: To assess the efficacy of the anti-estrogens tamoxifen and raloxifen in the medical management of persistent pubertal gynecomastia.
Study design: Retrospective chart review of 38 consecutive patients with persistent pubertal gynecomastia who presented to a pediatric endocrinology clinic. Patients received reassurance alone or a 3- to 9-month course of an estrogen receptor modifier (tamoxifen or raloxifene).
Results: Mean (SD) age of treated subjects was 14.6 (1.5) years with gynecomastia duration of 28.3 (16.4) months. Mean reduction in breast nodule diameter was 2.1 cm (95% CI 1.7, 2.7, P <.0001) after treatment with tamoxifen and 2.5 cm (95% CI 1.7, 3.3, P <.0001) with raloxifene. Some improvement was seen in 86% of patients receiving tamoxifen and in 91% receiving raloxifene, but a greater proportion had a significant decrease (>50%) with raloxifene (86%) than tamoxifen (41%). No side effects were seen in any patients.
Conclusion: Inhibition of estrogen receptor action in the breast appears to be safe and effective in reducing persistent pubertal gynecomastia, with a better response to raloxifene than to tamoxifen. Further study is required to determine that this is truly a treatment effect.
Like in the above study both tamoxifen and raloxifene works and reducing and shrinking all ready existing gyno but one does it better and has better effect overall as tamoxifen is known at lowering igf1 levels and other issues with prolactin side effects that raloxifene doesn’t do
The next thing that can help improve appearance of the nipple gland anvar or winstrol they have a anti prolactin lowering effect which can then give better appearance to the gland
Masteron I can say also has this effect as with it being a dht and giving a drying effect your nipples will also appear more stiff tighter less puffy
Conclusion here for the aesthetics of the nipples
raloxifene 60mg daily
winstrol or anavar 50mg daily
Masteron 400-600mg weekly
Sent from my SM-G998U using Tapatalk
