Is Uncle Z's HGH legit?

[heavyiron]

As u can read as above regarding rhGH a single measurement is meaningless,the accurate procedure in the clinic is taking samples every 20 min for 16-24.

If uncle z is ready to pay for the lab test I can analyse those blue tops according PhEur standard.

Then determine content and related substances. I need about 1-2 g product.

There are 3 main types of HGH testing, you are confusing the three tests. Growth Hormone is commonly tested to see bioequivalence based on log-transformed AUC and Cmax values. Many labs offer this to determine if further tests need to be made. The uncle Z blue tops increased my GH levels over 60 times baseline. pharmacokinetics of HGH are proven science and we have provided that science repeatedly but you choose to ignore it or are just plain ignorant. You are not fooling anyone with your agenda. Its clear you will do anything to tear down other sources even if it means deceiving members about common lab procedures.

Below is the pharmacokinetics of HGH once injected. It's obvious that GH blood testing is a REALITY.

The first treatment sequence received a 0.5 mL (2.92 mg) subcutaneous dose of r-hGH (Saizen®, Merck Serono) administered by standard needle and syringe (period 1) followed by administration of the same dose of rhGH using the cool.click™ 2 needle-free injection device (period 2). The second treatment sequence received 0.5 mL (2.92 mg) r-hGH administered by the cool.click™ 2 device (period 1) followed by administration of the same dose of r-hGH using a standard needle and syringe (period 2).

Full study below

http://www.biomedcentral.com/1472-6904/7/10

 

[Grozny]

There are 3 main types of HGH testing, you are confusing the three tests. Growth Hormone is commonly tested to see plasma levels. Almost all labs offer this to determine if further tests need to be made. The uncle Z blue tops increased my GH levels over 60 times baseline. pharmacokinetics of HGH are proven science and we have provided that science repeatedly but you choose to ignore it or are just plain ignorant. You are not fooling anyone with your agenda. Its clear you will do anything to tear down other sources even if it means deceiving members about common lab procedures.

Below is the pharmacokinetics of HGH once injected. It's obvious that GH blood testing is a REALITY.

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What confusion ?? Actually there is no any sense to make just a one blood test to verify the authenticity of GH that's my and scientifically point of view, it's totally worthless.

To have a stable results with your blood test the accurate procedure in the clinic is taking samples every 20 min for 16-24 h.

Actually I have a possibility to make labtest for any aas and GH now if u are interested then we can do it.

I m not bashing your thread but this result from your lab test is worthless.

 

[exphys88]

What confusion ?? Actually there is no any sense to make just a one blood test to verify the authenticity of GH that's my and scientifically point of view, it's totally worthless.

To have a stable results with your blood test the accurate procedure in the clinic is taking samples every 20 min for 16-24 h.

Actually I have a possibility to make labtest for any aas and GH now if u are interested then we can do it.

I m not bashing your thread but this result from your lab test is worthless.

Testing every 20 min multiple times is how you test endogenous hgh levels. The study above shows how they test serum hgh levels after injecting exogenous hgh. After 2-4 hours of exogenous hgh being injected there should be a spike in serum hgh levels. Heavy wasn't measuring his natural hgh levels, he was measuring the response To injecting hgh.

 

[Grozny]

Testing every 20 min multiple times is how you test endogenous hgh levels. The study above shows how they test serum hgh levels after injecting exogenous hgh. After 2-4 hours of exogenous hgh being injected there should be a spike in serum hgh levels. Heavy wasn't measuring his natural hgh levels, he was measuring the response To injecting hgh.

please is there someone with knowledge here ...

 

[exphys88]

please is there someone with knowledge here ...

Can you provide a scientific explanation for his serum hgh levels being so elevated, other than that he injected exogenous hgh? You are ignoring this important piece of the puzzle.

 

[yzfrr11]

To have a stable results with your blood test the accurate procedure in the clinic is taking samples every 20 min for 16-24 h.

The best time to catch your peak HGH level is around 3-4 hours post a singe bolus SC injection. While it is true that the metabolic half life of rHGH is only 30 minutes, the rate of absorption of the dose from the soft tissues into the venous capillary network is limiting the rate of appearance of the HGH into the serum. So, HGH demonstrates second order pharmacokinetics.

Now, if you are talking about naturally released GH from your anterior pituitary, you are absolutely correct that a single serum level is totally worthless because the release of the hormone is very fleeting and short lived. However, after a bolus injection, a peak serum level is observed at 3-4 hours. And in this scenario, a single serum level has been validated in the peer reviewed scientific literature.

 

[exphys88]

The best time to catch your peak HGH level is around 3-4 hours post a singe bolus SC injection. While it is true that the metabolic half life of rHGH is only 30 minutes, the rate of absorption of the dose from the soft tissues into the venous capillary network is limiting the rate of appearance of the HGH into the serum. So, HGH demonstrates second order pharmacokinetics.

Now, if you are talking about naturally released GH from your anterior pituitary, you are absolutely correct that a single serum level is totally worthless because the release of the hormone is very fleeting and short lived. However, after a bolus injection, a peak serum level is observed at 3-4 hours. And in this scenario, a single serum level has been validated in the peer reviewed scientific literature.

well said. He's ignoring all of this though.

 

[XYZ]

well said. He's ignoring all of this though.

There is a reason for that, he doesn't know and he cuts and pastes almost everything.

 

[yzfrr11]

There is a reason for that, he doesn't know and he cuts and pastes almost everything.

Maybe he doesn't understand English?

 

[BP2000]

nice work H! You have IGF-1 level's of a young man

 

[XYZ]

Maybe he doesn't understand English?

Who knows, I love that he states he's from CO.

 

[ellfrog007]

Thanks for this post.A big help.

 

[heavyiron]

The best time to catch your peak HGH level is around 3-4 hours post a singe bolus SC injection. While it is true that the metabolic half life of rHGH is only 30 minutes, the rate of absorption of the dose from the soft tissues into the venous capillary network is limiting the rate of appearance of the HGH into the serum. So, HGH demonstrates second order pharmacokinetics.

Now, if you are talking about naturally released GH from your anterior pituitary, you are absolutely correct that a single serum level is totally worthless because the release of the hormone is very fleeting and short lived. However, after a bolus injection, a peak serum level is observed at 3-4 hours. And in this scenario, a single serum level has been validated in the peer reviewed scientific literature.

Correct. He completely missed this point.

Testing to diagnose GH abnormalities often involves either a GH stimulation test (many measurements every 20 min or so) or a GH suppression test. These are used to evaluate pituitary response and changes in GH levels.We could care less about these tests because we are NOT testing for pituitary response.

 

[Grozny]

The best time to catch your peak HGH level is around 3-4 hours post a singe bolus SC injection. While it is true that the metabolic half life of rHGH is only 30 minutes, the rate of absorption of the dose from the soft tissues into the venous capillary network is limiting the rate of appearance of the HGH into the serum. So, HGH demonstrates second order pharmacokinetics.

Now, if you are talking about naturally released GH from your anterior pituitary, you are absolutely correct that a single serum level is totally worthless because the release of the hormone is very fleeting and short lived. However, after a bolus injection, a peak serum level is observed at 3-4 hours. And in this scenario, a single serum level has been validated in the peer reviewed scientific literature.

I'm talking exclusively about taking external GH, there is no any concrete answer even with blood test to detect the plasma level (external rhGH) , cuz there is no reliable test to distinguish between "external" and endogenous hGH.

Per example if heavy has made a blood test before and after taking his GH that would be a start for something that we can discuss cuz we have a reference peak.

 

[Grozny]

There is a reason for that, he doesn't know and he cuts and pastes almost everything.

u have all symptoms and signs of dyslexia reading difficulties, writing ... and just for u

Dyslexia

From Wikipedia, the free encyclopedia
This article is about developmental dyslexia. For acquired dyslexia, see Alexia (acquired dyslexia).

Dyslexia is a very broad term defining a learning disability that impairs a person's fluency or comprehension accuracy in being able to read,[1] and which can manifest itself as a difficulty with phonological awareness, phonological decoding, orthographic coding, auditory short-term memory, or rapid naming.[2][3] Dyslexia is separate and distinct from reading difficulties resulting from other causes, such as a non-neurological deficiency with vision or hearing, or from poor or inadequate reading instruction.[4][5] It is believed that dyslexia can affect between 5 to 10 percent of a given population although there have been no studies to indicate an accurate percentage.[6][7][8]
There are three proposed cognitive subtypes of dyslexia: auditory, visual and attentional.[7][9][10][11][12][13] Reading disabilities, or dyslexia, is the most common learning disability, although in research literature it is considered to be a receptive language-based learning disability.[14]
Accomplished adult dyslexics may be able to read with good comprehension, but they tend to read more slowly than non-dyslexics and may perform more poorly at nonsense word reading (a measure of phonological awareness) and spelling.[15] Dyslexia is not an intellectual disability, since dyslexia and IQ are not interrelated, as a result of cognition developing independently.[1

 

[XYZ]

u have all symptoms and signs of dyslexia reading difficulties, writing ... and just for u

Dyslexia

From Wikipedia, the free encyclopedia
This article is about developmental dyslexia. For acquired dyslexia, see Alexia (acquired dyslexia).

Dyslexia is a very broad term defining a learning disability that impairs a person's fluency or comprehension accuracy in being able to read,[1] and which can manifest itself as a difficulty with phonological awareness, phonological decoding, orthographic coding, auditory short-term memory, or rapid naming.[2][3] Dyslexia is separate and distinct from reading difficulties resulting from other causes, such as a non-neurological deficiency with vision or hearing, or from poor or inadequate reading instruction.[4][5] It is believed that dyslexia can affect between 5 to 10 percent of a given population although there have been no studies to indicate an accurate percentage.[6][7][8]
There are three proposed cognitive subtypes of dyslexia: auditory, visual and attentional.[7][9][10][11][12][13] Reading disabilities, or dyslexia, is the most common learning disability, although in research literature it is considered to be a receptive language-based learning disability.[14]
Accomplished adult dyslexics may be able to read with good comprehension, but they tend to read more slowly than non-dyslexics and may perform more poorly at nonsense word reading (a measure of phonological awareness) and spelling.[15] Dyslexia is not an intellectual disability, since dyslexia and IQ are not interrelated, as a result of cognition developing independently.[1

LOL, if you say so sweet cheeks.

 

[BP2000]

yeah he should have gotten igf-1 test done before as a reference but we know that going on hrt can raise levels 30% or more. Then adding Z's HGH raised his levels from whatever they were after test replacement to now 350 which is a level of a 20 yo.

 

[heavyiron]

My baseline IGF-1 was 163 ng/ml.

I'm in my mid forties.

 

[yzfrr11]

there is no reliable test to distinguish between "external" and endogenous hGH.

Not true.

Any GH level greater than 3.0 is exogenous HGH - because even after an insulin/arginine challenge test, a serum HGH of greater than 3.0 is not possible.

 

[Grozny]

Bro GH measurements are highly variable and so a single high reading has no clinical or forensic value.

For this case the IGF-I measurement is more stable and is high. This is probably suggestive of the GH administration however, there are a number of caveats:

1) Sample must be measured twice with two separate assays for both P- III-NP.

2) The laboratory gives a single reference range and as age is a major determinant of IGF-I, our function gives an age correction; it is not clear whether the reference range given by the lab is appropriate for this man

etc etc ...

 

[heavyiron]

Bro GH measurements are highly variable and so a single high reading has no clinical or forensic value.

For this case the IGF-I measurement is more stable and is high. This is probably suggestive of the GH administration however, there are a number of caveats:

1) Sample must be measured twice with two separate assays for both P- III-NP.

2) The laboratory gives a single reference range and as age is a major determinant of IGF-I, our function gives an age correction; it is not clear whether the reference range given by the lab is appropriate for this man

etc etc ...

The Uncle Z bluetops elevated both my HGH and IGF-1 levels above the reference range.

1) I will retest again soon and post the results.

2) The lab DID factor in my age. They used 41-45 years old.

 

[Grozny]

The Uncle Z bluetops elevated both my HGH and IGF-1 levels above the reference range.

1) I will retest again soon and post the results.

2) The lab DID factor in my age. They used 41-45 years old.

is it possible to send to one of my labs a sample of your blood to test with our method then we will publish results here ??

 

[Grozny]

is it possible to send to one of my labs a sample of your blood to test with our method then we will publish results here ??

laboratory analyzing will be done for free are u interested ???

 

[heavyiron]

LabCorp is a reputable lab in the USA. I will show Prince my original lab work so you guys know I am being 100% honest. I will see him Saturday.

 

[Grozny]

LabCorp is a reputable lab in the USA. I will show Prince my original lab work so you guys know I am being 100% honest. I will see him Saturday.

I was just thinking to analyse your blood with another selective method, exclusively sensitive for the GH detection.

 

[independent]

is it possible to send to one of my labs a sample of your blood to test with our method then we will publish results here ??

Dont do it heavy, he wants your dna to make a clone of you for a personal sex slave.

 

[Vibrant]

Dont do it heavy, he wants your dna to make a clone of you for a personal sex slave.

I was thinking he was planning a murder and he needed dna to plant.

 

[Ezskanken]

Thanks for doing all this Heavy!

 

[Pony]

Hey guys, the shit works - hows that for a fucking test result?