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DNP Logs

bigbenj

bigbenj

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There has been a lot of talk about it around here, so..

Another member and myself will be running DNP, keeping a log of it, and getting blood work done 5 weeks after the last run.

Not sure of the exact start date yet, but we'll keep you informed. This will be a great tool for many people, the two of us included.

The plan is to run it twice, as so, with a week break in between:

Days 1-3 200mg/day
Days 4-14 400mg/day

one week break and repeat.

We hope to learn a lot along the way, and to shed some light on this controversial compound. Stay tuned.
 
It was actually cool how it came about. I've been talking about it here, and a little bit with him in private. He told me he got his stuff and that we should run it together and share the misery haha.

We will be using stuff from the same supplier as well. So that there are no discrepancies in terms of quality.
 
What was the diet and fluid intake like of these two young men? How much were they ingesting? What other activities were they involved in?

I'm not trying to play it off, I just want answers. Answers that I'm not finding from anyone on this board. So now, its time to step up to the plate and play ball.
 
Since no one can give concrete answers to any of these stories, I will use his as an auto reply:


bigbenj said:
What was the diet and fluid intake like of these two young men? How much were they ingesting? What other activities were they involved in?

I'm not trying to play it off, I just want answers. Answers that I'm not finding from anyone on this board. So now, its time to step up to the plate and play ball.
Click to expand...
 
I have no clue what any of these people did. They said the girl ingested a large quantity. Well, how large exactly is large?
 
Listen, I can post from webmd, pubmed, wiki, all that shit, all day, just to prove whatever I want to. It's worthless to me, when every report conflicts the next one.
 
If I come out of this shredded, I'm going to say fuck off.
If I die, I hope you all come to my funeral.
 
nice knowing ya benj, RIP j/k... Im interested in seeing your log but Id be way to skeched to try my self,
 
I missed that

"The court heard that Selena had taken a gram of the drug, popular with body builders, the day before she died – a dose more than five times the amount taken by even the most extreme bodybuilders.
At 5ft 3ins tall but weighing 15 stone she was desperate to lose weight. She scoured the internet for pills before finding the drug"

If I'm reading this right, she was 5'3, 105lbs and took a gram? Well no shit....
You see what I'm talking about? I have no clue what these people are taking, then I found out this broad took a gram. She probably didn't know shit about it.
 
chucky1 said:
nice knowing ya benj, RIP j/k... Im interested in seeing your log but Id be way to skeched to try my self,
Click to expand...
This might be the time were my luck runs out and living on the edge finally gets the best off me.

fuck it, I'm going to power through this and come out lean and mean.
 
Vet Hum Toxicol. 2004 Oct;46(5):251-4.

Dying to be thin: a dinitrophenol related fatality.

McFee RB, Caraccio TR, McGuigan MA, Reynolds SA, Bellanger P.
Source

Long Island Regional Poison Control Center, Winthrop University Hospital, 107 Mineola Blvd, Mineola, NY 11501, USA.

Abstract

2, 4-dinitrophenol (DNP) was originally used as an explosive and later introduced in the 1930's to stimulate metabolism and promote weight loss. It's also a component of pesticides still available globally. Concerns about hyperpyrexia lead to DNP being banned as a dietary aid in 1938. A 22-y-old male presented to the Emergency Department (ED) with a change in mental status 16 h after his last dose of DNP. On admission he was diaphoretic and febrile with an oral temperature of 102 F, but lucid and cooperative. He became agitated and delirious. Intravenous midazolam was initiated with mechanical cooling. Pancuronium was administered later and the patient was intubated. Over the next hour the patient became bradycardic, then asystolic, and despite resuscitative efforts, died. Advertisements claim DNP safe at the dose our patient ingested. It is widely available and with the potential to cause severe toxicity is an understudied public health concern.

PMID:15487646 [PubMed - indexed for MEDLINE]

Dying to be thin: a dinitrophenol related fa... [Vet Hum Toxicol. 2004] - PubMed - NCBI
 
So, what we have here is, you're either trying to scare me into not using it, or you're going back on your whole "presenting unbiased information" bit, and only looking for the negative. hmmm..
 
J Anal Toxicol. 2006 Apr;30(3):219-22.

Two deaths attributed to the use of 2,4-dinitrophenol.

Miranda EJ, McIntyre IM, Parker DR, Gary RD, Logan BK.
Source

Washington State Toxicology Laboratory, Washington State Patrol, 2203 Airport Way South, Seattle, Washington 98134, USA.

Abstract

We report the cases of two individuals, one in Tacoma, WA, and the second in San Diego, CA, whose deaths were attributed to ingestion of 2,4-dinitrophenol (2,4-DNP). 2,4-DNP has historically been used as a herbicide and fungicide. By uncoupling mitochondrial oxidative phosphorylation, the drug causes a marked increase in fat metabolism that has led to its use to aid weight loss. Both cases reported here involved its use for this purpose. Features common to both cases included markedly elevated body temperature, rapid pulse and respiration, yellow coloring of the viscera at autopsy, history of use of weight loss or body building supplements, and presence of a yellow powder at the decedent's residence. Because of its acidic nature, the drug is not detected in the basic drug fraction of most analytical protocols, but it is recovered in the acid/neutral fraction of biological extracts and can be measured by high-performance liquid chromatography or gas chromatography-mass spectrometry. The concentration of 2,4-DNP in the admission blood samples of the two deaths reported here were 36.1 and 28 mg/L, respectively. Death in both cases was attributed to 2,4-DNP toxicity. Review of information available on the internet suggests that, although banned, 2,4-DNP is still illicitly promoted for weight loss.

PMID:16803658 [PubMed - indexed for MEDLINE]

Two deaths attributed to the use of 2,4-dinit... [J Anal Toxicol. 2006] - PubMed - NCBI
 
-Thresh: Alive and well after using DNP
-Vindicated: Alive and well after using DNP
-Anapolack: Alive and well after using DNP
-XYZ: Alive and well after using DNP
-GMO: Alive and currently using DNP

^All people who know what they're doing. All of them alive.
 
Toxicol Ind Health. 2011 May;27(4):323-7. Epub 2010 Dec 21.

2, 4-dinitrophenol poisoning caused by non-oral exposure.

Jiang Jiukun, Yuan Zhihua, Huang Weidong, Wang Jiezan.
Source

Department of Emergency, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Abstract

2, 4-Dinitrophenol (2, 4-DNP) is widely used in industry, but recently, poisoning through consumption for weight control has been frequently reported. We report the cases of two patients whose deaths were attributed to occupational and non-oral exposure of 2, 4-DNP. They were all poisoned through skin absorption and respiratory tract inhalation; common features were excessive sweating, hyperthermia, tachycardia, clouded consciousness and asystole. Because of the lack of specific early symptoms, effective antidotes and the means of washing the contamination from the skin, their arrival in hospital was delayed and the supportive therapy was ineffectual. Cardiac arrest occurred quickly and unexpected after admission.

PMID:21177364 [PubMed - indexed for MEDLINE]
 
According to the guy on the internet DNP is safer that hormones....


J Zhejiang Univ Sci B. 2011 Mar;12(3):189-92.
Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning.

Lu YQ, Jiang JK, Huang WD.
Source

Department of Emergency, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China. luyuanqiang@yahoo.cn

Abstract

OBJECTIVE:

To report clinical features and treatment of 16 cases of acute 2,4-dinitrophenol poisoning.
METHODS:

A total of 16 patients suffering from acute poisoning due to non-oral exposure to 2,4-dinitrophenol were sent to our hospital. Two died within 3 h after admission, while the other 14 responded to supportive treatment and hemoperfusion. Clinical features and treatment of the patients were retrospectively analyzed and presented.
RESULTS:

Fourteen patients recovered and were discharged after four to six weeks of treatment. No obvious poisoning sequelae were found in the three-month follow-up.
CONCLUSIONS:

Non-oral exposure to 2,4-dinitrophenol is toxic. Hemoperfusion and glucocorticoid treatments may be efficient measures to prevent mortality, but this requires further study.

PMID:21370503 [PubMed - indexed for MEDLINE]
PMCID: PMC3048933

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Yay, more useless posts that don't tell me anything about how they got to that state!!!
If you show me some studies/reports of people using 400mg, including their diet and fluid intake, and dropping dead, I will drop the idea altogether.
 
I'm not denying these reports, as they obviously happened, but they aren't giving me and variables.
 
bigbenj said:
So, what we have here is, you're either trying to scare me into not using it, or you're going back on your whole "presenting unbiased information" bit, and only looking for the negative. hmmm..
Click to expand...
Many guys here are telling you DNP is safe according to studies. One or two guys are telling you to look at the evidence that it's dangerous. If you don't like the evidence just ignore it. I also have seen ZERO modern scientific studies stating DNP is safe for human consumption.
 
J Med Toxicol. 2011 Sep;7(3):205-12.

2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death.

Grundlingh J, Dargan PI, El-Zanfaly M, Wood DM.
Source

Emergency Medicine, Whittington Hospital, London, UK.

Abstract

2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects. DNP is sold mostly over the internet under a number of different names as a weight loss/slimming aid. It causes uncoupling of oxidative phosphorylation; the classic symptom complex associated with toxicity of phenol-based products such as DNP is a combination of hyperthermia, tachycardia, diaphoresis and tachypnoea, eventually leading to death. Fatalities related to exposure to DNP have been reported since the turn of the twentieth century. To date, there have been 62 published deaths in the medical literature attributed to DNP. In this review, we will describe the pattern and pathophysiology of DNP toxicity and summarise the previous fatalities associated with exposure to DNP.

PMID:21739343 [PubMed - indexed for MEDLINE]
 
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