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S4 sounds too good to be true ? but it isn?t. The trick is that S4 is very difficult to manufacture, thus hard to find in a quality form. Our S4 is manufactured to the highest standard, allowing for the highest bioavailibility. Its made to 99% purity and dosed appropriately to ensure a true 50mg/ml dosage.
What is a SARM anyway?
A SARM (Selective Androgen Receptor Modulator) selectively binds to androgen receptors, allowing it to exert the benefits of an androgen in the absence of many of the undesired effects. To better understand this, one must look at a traditional androgen ? which binds in indiscriminately to androgen receptors. The primary example of a traditional androgen would be testosterone. Testosterone is non selective in its binding activity (it will bind to androgen receptors anywhere), so all the effects an androgen will exert would be observed in your research. Some examples of this would be testicular atrophy, hpta ?shut down?, decrease in bone mineral density, etc.
S4 , on the other hand , primarily (selectively) binds to androgen receptors in muscle tissue , allowing for increases in muscle mass and decreases in body fat comparable to a traditional androgen (testosterone), without the other effects mentioned above being observed. Its gets better. While S4 when manufactured properly is highly bioavaiable when taken orally, the traditional liver toxicity associated with oral steroids will not be observed.
Refs:
Gao W, Kim J, Dalton JT. Pharmacokinetics and pharmacodynamics of nonsteroidal androgen receptor ligands. Pharmaceutical Research. 2006 Aug;23(8):1641-58.
Yin D, Gao W, Kearbey JD, Xu H, Chung K, He Y, Marhefka CA, Veverka KA, Miller DD, Dalton JT. Pharmacodynamics of selective androgen receptor modulators. Journal of Pharmacology and Experimental Therapeutics. 2003 Mar;304(3):1334-40
Check it out Liquid S4 30mL 50mg/mL
What is a SARM anyway?
A SARM (Selective Androgen Receptor Modulator) selectively binds to androgen receptors, allowing it to exert the benefits of an androgen in the absence of many of the undesired effects. To better understand this, one must look at a traditional androgen ? which binds in indiscriminately to androgen receptors. The primary example of a traditional androgen would be testosterone. Testosterone is non selective in its binding activity (it will bind to androgen receptors anywhere), so all the effects an androgen will exert would be observed in your research. Some examples of this would be testicular atrophy, hpta ?shut down?, decrease in bone mineral density, etc.
S4 , on the other hand , primarily (selectively) binds to androgen receptors in muscle tissue , allowing for increases in muscle mass and decreases in body fat comparable to a traditional androgen (testosterone), without the other effects mentioned above being observed. Its gets better. While S4 when manufactured properly is highly bioavaiable when taken orally, the traditional liver toxicity associated with oral steroids will not be observed.
Refs:
Gao W, Kim J, Dalton JT. Pharmacokinetics and pharmacodynamics of nonsteroidal androgen receptor ligands. Pharmaceutical Research. 2006 Aug;23(8):1641-58.
Yin D, Gao W, Kearbey JD, Xu H, Chung K, He Y, Marhefka CA, Veverka KA, Miller DD, Dalton JT. Pharmacodynamics of selective androgen receptor modulators. Journal of Pharmacology and Experimental Therapeutics. 2003 Mar;304(3):1334-40
Check it out Liquid S4 30mL 50mg/mL

