malcolm383
Registered
Have any of you guys run t3 and DNP together? I have used DNP 2 times so far and have really liked it. And I heard good things about t3. Do you think I could run them together safely??
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t3 + DNP
- Thread starter malcolm383
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malcolm383
Registered
I'm very aware of that. I have used it safely before. Iv read all about it and talked to numerous people before I ever used it.
~RaZr~
Elite Member
Is this following a major bulk or are you running it with something to preserve muscle mass like SD, metha-drol or anabolics?
Not trying to sound like an ass, but T3 isn't something you want to mess with (even though you SAY you have ran DNP and know "a lot" about it).
Not trying to sound like an ass, but T3 isn't something you want to mess with (even though you SAY you have ran DNP and know "a lot" about it).
malcolm383
Registered
3 to 4 weeks at 500 mgs a day. Last time I ran it at 600 mgs a day for 3 weeks and felt fine at the end. Since it lowers your t3 I was gonna run that at 75 mcg a day with it.
Digitalash
Registered
I wouldn't consider it if you're not running AAS with it IMO
malcolm383
Registered
No I'm just trying to get my body fat back down to 12% I'm at 16% now.
malcolm383
Registered
I have 4 bottles of QV test e I just didn't wanna pin that till I got my body fat back down.
Damn man i can only run it 10 days max at that dose. Haha
Yeah it shuts down the conversion from t4 to t3. You won't need it right away , keep track of your temp and when you see your temp slowly lowering back to normal then that means your t3 is starting to shut down. That's when I would then introduce the t3. 50-75mcg would be fine.
malcolm383
Registered
but I cut about 20 pounds. Thanks for the advice broYou could just run it the first 3-4 weeks of the test e you got. It's gonna take 3-4 weeks to kick in and start seeing big gains so get your BF down then. Will preserve your muscle and then get huge.
malcolm383
Registered
^ I agree. The Thyroid gland should not be messing around with. Thyroxine (T3) Is hydrophobic when trying to enter the target cell so it uses secondary messengers via G Proteins (cAMP) which later enter the nucleus for mRNA transcription and increase ATP production. It also controls calcitonin which affect your calcium ions and the enzymes activating phosphorylation that set up positive feedback loop rapidly elevates. so it basically wont allow your body to release calcium out of your skeletal tissue cells. And to part that need it.
I dont even know what DNP is.
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there is nothing wrong about running low doses of T3 with aas cycle...
there is also no proof about running T3 and shutting your natural production, it recovers after a period of time...
It is just a myth.
But Thyroid work in sinc and the Parathyroid releasing T4 (triiodothyronine) located posterior to the thyroid deals with your Iodine. Ever heard the saying if you ever survive a nuke several miles form ground zero and were exposed to radiation. The first to go is they Thyroid. Has something to do with iodine.
But maybe a low dose wont affect it too much. I really dont know. Just stating the functions.
You use DNP and your worried about a little T3. There is NO reason to use DNP a known POISON to get to 12% bodyfat . Come on Bro you can do that much safer with the traditional methods. Thats the problem with risky stuff sometimes, people say well I did it and I'm fine. Well maybe you didn't just keel over dead but that doesn't mean to keep doing it. The price to be paid comes much later !
~RaZr~
Elite Member
Um....I think you quoted the wrong statement boss.
vindicated346
Registered
There is far too much misinformation and scaremongering amongst the forums in reference to DNP. It's often spread by people who haven't actually ran the product itself.
Running low dose t3 with a cycle of dnp is completely fine. Studies have shown that T3 down regulation is relevant to dosage taken. generally in the 400-600mg range, this usually occurs around the 1 week period.
Another option instead of the higher dosed cycles, would be to run a lower dose of 200mg a day for a longer run, and there fore not needing the addition of T3 to counteract thyroid shut down.
It always makes me smile when I see guys who run AAS, to get bigger,stronger, in a shorter amount of time tell someone to not run products such as DNP because its the easy way out, or something to that affect
Im currently running my own dnp at 400mg a day for about 3 weeks now. while running 500mg test P, and 300mg tren A, I'm stronger than when I started *obviously* the, but im about 22lbs lighter
Running low dose t3 with a cycle of dnp is completely fine. Studies have shown that T3 down regulation is relevant to dosage taken. generally in the 400-600mg range, this usually occurs around the 1 week period.
Another option instead of the higher dosed cycles, would be to run a lower dose of 200mg a day for a longer run, and there fore not needing the addition of T3 to counteract thyroid shut down.
It always makes me smile when I see guys who run AAS, to get bigger,stronger, in a shorter amount of time tell someone to not run products such as DNP because its the easy way out, or something to that affect
Im currently running my own dnp at 400mg a day for about 3 weeks now. while running 500mg test P, and 300mg tren A, I'm stronger than when I started *obviously* the, but im about 22lbs lighter
state these "studies"
vindicated346
Registered
TJTJ, I stand corrected on the "study"..perhaps an article wouldve been a better word, it is from a well known member of several boards with extensive research on the subject, he states
Conciliator post on t3 and DNP:
"DNP doesn't shut down the thyroid. This is a common myth. AAS and DNP have a similar effect on thyroid, through a similar mechanism of action. While androgens reduce the concentration of thyroid binding globulin (TBG), DNP occupies thyroid binding proteins, which has the same result... less protein to bind to thyroid. This may initially result in higher serum levels and accelerated clearance, but after a short term alteration in thyroid function a new steady state is soon reached in which thyroid function is normal, despite potentially reduced serum levels of total T4 and total T3. As one paper on DNP explained, "this action could lower the total hormone concentration in serum but should have no persistent effect on thyroid function". This means that even though the level of thyroid hormones in the blood can potentially be lower than normal, thyroid function will still be normal. What I've seen happen most of the time, however, is that thyroid levels hardly change.
There's a case study that's often posted as evidence for thyroid dysfunction from DNP, but I'm of the opinion that the bodybuilders in question had low thyroid levels not because of the DNP, but because they were taking T3 during their cycle. Exogenous T3 definitely will suppress endogenous production. I had a Norwegian translate the paper and it was unclear why they had low thyroid levels. They didn't test for reverse thyroid when they could have, which would have made the cause clearer.
I also have a friend who's a doctor of internal medicine who ran 600mg/day of crystal DNP for 3-4 months (went from 320 lbs down to the mid 200's). He gave himself frequent blood tests and said his thyroid didn't budge. I've heard feedback from several others who did blood work showing the same thing.
I'm just not convinced that DNP results in any thyroid dysfunction. You definitely do NOT need to take thyroid along with DNP. Considering how notoriously catabolic thyroid is, I'd recommend leaving it out of your dieting plan."
Conciliator post on t3 and DNP:
"DNP doesn't shut down the thyroid. This is a common myth. AAS and DNP have a similar effect on thyroid, through a similar mechanism of action. While androgens reduce the concentration of thyroid binding globulin (TBG), DNP occupies thyroid binding proteins, which has the same result... less protein to bind to thyroid. This may initially result in higher serum levels and accelerated clearance, but after a short term alteration in thyroid function a new steady state is soon reached in which thyroid function is normal, despite potentially reduced serum levels of total T4 and total T3. As one paper on DNP explained, "this action could lower the total hormone concentration in serum but should have no persistent effect on thyroid function". This means that even though the level of thyroid hormones in the blood can potentially be lower than normal, thyroid function will still be normal. What I've seen happen most of the time, however, is that thyroid levels hardly change.
There's a case study that's often posted as evidence for thyroid dysfunction from DNP, but I'm of the opinion that the bodybuilders in question had low thyroid levels not because of the DNP, but because they were taking T3 during their cycle. Exogenous T3 definitely will suppress endogenous production. I had a Norwegian translate the paper and it was unclear why they had low thyroid levels. They didn't test for reverse thyroid when they could have, which would have made the cause clearer.
I also have a friend who's a doctor of internal medicine who ran 600mg/day of crystal DNP for 3-4 months (went from 320 lbs down to the mid 200's). He gave himself frequent blood tests and said his thyroid didn't budge. I've heard feedback from several others who did blood work showing the same thing.
I'm just not convinced that DNP results in any thyroid dysfunction. You definitely do NOT need to take thyroid along with DNP. Considering how notoriously catabolic thyroid is, I'd recommend leaving it out of your dieting plan."
And how is that different from clen, albuterol or EC stacks?
~RaZr~
Elite Member
Probably because DNP works. Some people use ECA for energy, ability to breath better (ephedrine) and fat loss. "Alby" and "Clen" are bronchodilators that have an off-label, fat burning use.
I'm not arguing, just pointing out that DNP really has no other use other than instant fat loss. You can eat like total dog shit, not work out and still lose weight.
I'm not arguing, just pointing out that DNP really has no other use other than instant fat loss. You can eat like total dog shit, not work out and still lose weight.
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No bro thats not even close to the truth. The amount of cardio and dieting you would haVe to do to come close to Losing the amount of fat on a 8-14 day dnp run would take about 2 months and you would still end up losing alot more muscle.
It's no different then taking aas to get bigger.
To get the full benefits of AAS, you have to eat and train your ass off.
To get the full benefits of DNP, you just need to sit on your couch...
Again, Ill ask the OP to post his diet, and possibly his reasons behind using DNP.
Please explain to me why you felt the need to incorporate DNP?
AAS and DNP are not on the same level. AAS is used to break past genetic limitations(although not always used that way). DNP is poison. DNP is not used to break past limitations, its for people who are lazy and want to take a shortcut, because they dont have the dedication to make the changes through diet and cardio.
Are you really going to put poison in your body so that you can slack on diet and cardio?
vindicated346
Registered
going to have to disagree..MOST, and I'll say it again..MOST guys on here run gear for all the benefits its gives. muscle strength, size, definition to a degree, it is NOT to break through a genetic limitation, we take it because naturally it would take longer, to just eat, train and get that 5-10lbs increase in 3 to 4 months, that would naturally take a year or two.
DNP when used correctly, is second to none in its ability to burn fat. Imagine an on average increase of 35-60% increase in metabolism, COMBINED with proper diet, and cardio if one were up to it, the results you could gain.
and dont get started on the poison this and poison that..considering some of the side effects that AAS carry with them. not to mention all the research that actually show DNP's beneficial/protective effects
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=16754295
The mitochondrial uncoupler 2,4-dinitrophenol attenuates tissue damage and improves mitochondrial homeostasis following transient focal cerebral ischemia.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
Regulation of human male germ cell death by modulators of ATP production.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
Energy requirement for degradation of tumor-associated protein p53.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
The mitochondrial uncoupling agent 2,4-dinitrophenol improves mitochondrial function, attenuates oxidative damage, and increases white matter sparing in the contused spinal cord.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15672630
DNP when used correctly, is second to none in its ability to burn fat. Imagine an on average increase of 35-60% increase in metabolism, COMBINED with proper diet, and cardio if one were up to it, the results you could gain.
and dont get started on the poison this and poison that..considering some of the side effects that AAS carry with them. not to mention all the research that actually show DNP's beneficial/protective effects
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=16754295
The mitochondrial uncoupler 2,4-dinitrophenol attenuates tissue damage and improves mitochondrial homeostasis following transient focal cerebral ischemia.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
Regulation of human male germ cell death by modulators of ATP production.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
Energy requirement for degradation of tumor-associated protein p53.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
The mitochondrial uncoupling agent 2,4-dinitrophenol improves mitochondrial function, attenuates oxidative damage, and increases white matter sparing in the contused spinal cord.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15672630
