Vidalista 60 mg contains PDE 5 inhibitor Tadalafil. Nitric oxide is released into the penis' smooth muscular tissue on sexual excitement, causing an erection. Nitric oxide increases cGMP synthesis, which governs blood vessel dilatation and contraction. Increased cGMP causes a hard erection. However, PDE 5 prevents erections. Tadalafil in Vidalista 60 for sale inhibits PDE 5 and cGMP breakdown. This makes penis blood flow easy. Pressure builds as blood travels to the penis. This causes erection.