Fruit will affect you the same as anything with fructose and glucose. Like table sugar, or soda pop. The difference is you are unlikely to consume as much fructose and glucose from eating whole fruit as you could be if you were drinking juice or pop, or eating a lot of sucrose in other forms.
It's calories; it's sugar, about half of which is fructose. Fruit, however, is nourishing - particularly colourful fruits such as berries. Colourful berries contain antioxidants and fibre, and tend to be lower in carbohydrate than other types of fruit, such as apples, oranges and bananas.