tren ace liver toxic?

[nick52]

i wanted to bring this question to you guys so i could hear from experience i just started my 2nd cycle, first cycle sus and decca so now id like to cycle sus and tren a, i have to be careful with anything that is liver toxic,but even so im thinking 300mg, 75eod , 6 weeks, how much damage if any, the public oppinion is that all steroids are dangerous but aspirin can be dangerous if its abused
thanks fellas

 

[redz]

I think it can be hard on the kidneys more than anything.

 

[vannesb]

i wanted to bring this question to you guys so i could hear from experience i just started my 2nd cycle, first cycle sus and decca so now id like to cycle sus and tren a, i have to be careful with anything that is liver toxic,but even so im thinking 300mg, 75eod , 6 weeks, how much damage if any, the public oppinion is that all steroids are dangerous but aspirin can be dangerous if its abused
thanks fellas

I have some Liver issues and that is 1 compound I will not use for that reason. I would get blood work done see what you enzymes etc look like and if everything is in line then I would go for it. Mine are always elavated so I stay away from it. Dont run many orals and when I do for normaly 4 weeks for the same reason since it passes thru your liver twice. I drink plenty of water, also take liv support etc and then blood work at the end of cycle.

 

[nick52]

vanesb
my liver enzymes are also elevated, ive stayed away from the orals, but ive started the tren at 50mg eod,just want to run it for 4 weeks

 

[XYZ]

Tren Ace is HIGHLY liver toxic.

 

[nick52]

im already a week in grabbed some on cycle support and liver support so far so good any bad signs and i will end this tren cycle

 

[charley]

Yo Nick.........
Answer: Trenbolone acetate preperations are toxic to both liver and kidney tissue. The extent is a matter of period of administration for the most part. The reasons are strange but true.

At one time there were the many black-market preperations of Finaplix, FinaJect and others. Most of these contained simple ground Finaplex-H implants...as most are painfully aware. With the process (if you can refer to a caveman approach as a process. The idea of "I have a rock and can make my own AAS" is not a good one) came many foreign non-kidney-friendly materials, some of which were non-soluable. The use of Fina-kits eleminated some of the material concerns due to the use of benzyl alcohol as a solvent to seperate the binders from the AAS in Finaplex-H implants. But there is another concern. The EOD or ED administration of trenbolone acetate preperations also means an accumulation of benzyl alcohol (which is quite high in these kits). Personally I felt that in itself this would not be a huge concern. Unfortunately athlete liver and kidney stress markers consistantly showed in those who utilized the drug. (A little research to discuss)

TR-343
Toxicology and Carcinogenesis Studies of Benzyl Alcohol (CAS No. 100-51-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Chemical Formula: C7H8O - 3D Structure*

Toxicology and carcinogenesis studies of technical-grade benzyl alcohol (99% pure), a textile dye additive, solvent, and food flavoring agent, were conducted by administering the chemical by gavage in corn oil vehicle to groups of F344/N rats and B6C3F1 mice of each sex for 16 days, 13 weeks, or 2 years.

Short-Term Studies:
In 16-day studies, all five male and five female rats and mice dosed with 2,000 mg/kg benzyl alcohol died. Two of five male and 3/5 female rats and 1/5 male and 2/5 female mice dosed with 1,000 mg/kg died. Rats and mice of each sex in the two highest dose groups were lethargic after dosing. Other toxic responses to benzyl alcohol in these dose groups included blood around the mouth and nose, subcutaneous hemorrhages, and blood in the urinary and gastrointestinal tracts of rats and blood in the urinary bladder of mice. Animals administered lower doses of benzyl alcohol (125, 250, or 500 mg/kg) had no compound-related histologic lesions.

Doses selected for the 13-week studies were 0, 50, 100, 200, 400, and 800 mg/kg for rats and mice. Eight of 10 male rats dosed with 800 mg/kg died during weeks 7 and 8; four of these deaths were described as gavage related. Rats dosed with 800 mg/kg exhibited clinical signs indicative of neurotoxicity including staggering, respiratory difficulty, and lethargy. Hemorrhages occurred around the mouth and nose, and there were histologic lesions in the brain, thymus, skeletal muscle, and kidney.

In truth I now feel that it is the accumulative benzyl alcohol that had altered the liver and kidney markers disfavorably far more so than the trenbolone itself. One must remember that the amount of benzyl alcohol in 1ml of most kit preperations is several times higher than an entire 10ml vial of testosterone enanthate.

...........charley

 

[BigBird]

^^ To Charley:

I'm sure not many aas users (even experienced ones) consider the toxicity of the BA content of compounds; in this case, Tren Ace. Thanks for highlighting this aspect.

 

[nick52]

thanks charlie
i had also saw that study,and that was something i didnt know, im seriosly considering just raising my dosage of test,since testosterone is relativly safe

 

[charley]

Nick......if your on 'trt' , just boost your 'mgs' .....if your doing 300mgs go up to 600mgs for 8 or 10wks...then back to 300 mgs....no pct

....charley

 

[nick52]

thanks charley
thats what im gonna do,since testosterone is relatively safe and i have 3bottles of omega suspension im thinking ofgoing with 50mg-100mg pre workout on top of500mg of sus 125 eod thanks charlie ,i like tren ,the risk may not be worth the benefit

 

[charley]

thanks charley
thats what im gonna do,since testosterone is relatively safe and i have 3bottles of omega suspension im thinking ofgoing with 50mg-100mg pre workout on top of500mg of sus 125 eod thanks charlie ,i like tren ,the risk may not be worth the benefit

..Nick...suspension in not cyp or ent.....for one thing it can be painful..




Testosterone Suspension is the oldest steroid ever created. Basically it is pure testosterone without any ester attached to it. This has its disadvantages because without any ester the testosterone wonâ??????t last very long in the body and will probably need to be injected every day, even multiple times a day. The major advantage of pure testosterone is that users get exactly the amount of testosterone that the vial says is there and because of testosterone suspensionâ??????s pure anabolic/androgenic ratio of 1:1, it is the most potent testosterone you can put in your body by weight available.
Testosterone is the male sex hormone responsible for many of the physical and emotional traits of men. It creates the deeper voices, sex drive, aggression and, of coarse, larger muscles in men. Testosterone makes the muscles retain more nitrogen, which in turn makes the muscle synthesize proteins better, producing larger muscles.
The downside to testosterone steroids is that they aromatize, or turn into estrogen, in the body. When the body has too much estrogen it begins to take on female characteristics â?????? gynocomastia, water retention, fat gain, loss of sex drive and testicular shrinkage are all most certain side effects of taking testosterone and letting it aromatize in the body.
Testosterone suspension is an injectable preparation containing testosterone (no ester) in a water base. Since testosterone is not highly water soluble, the steroid will noticeably separate from the solution when the vial is left to sit. A quick shake will put the drug back into suspension, at least temporarily, so that it can be withdrawn in a consistent dosage. Although it may contain testosterone without the benefit of an ester, and contrary to popular belief, the microcrystal design of this injectable will sustain an elevated testosterone release for 2-3 days. Clearly the suspension we see today is not the basic water plus testosterone design used in the 1940′s. And since the drug will not leave circulation in a matter of hours, it is obviously useful.
Among bodybuilders, ???suspension??? is known to be an extremely potent mass agent. It is often ranked as the most powerful injectable steroid available, resulting in an incredibly rapid gain of muscle mass and strength. This is largely due to the very fast action of this drug, as the water-based steroid will begin to enter the blood stream almost immediately after an injection is given. Unlike longer esters such as enanthate or cypionate which take weeks for blood levels to reach maximiun theraputic levels, with suspension it is just a matter of days. Clearly the anabolic effect of this testosterone will be realized much more quickly than we would expect with an oil based (esterified) preparation.
It is also important to remember that 100mg of a testosterone ester is not equivalent to 100mg testosterone of pure testosterone (as in suspension). When an ester is present, its weight is obviously included in the preparation???s milligram total. Looking at Testosterone enanthate, 100mg of this compound equates to only 72mg of raw testosterone. So the bodybuilder who uses 400mg of enanthate weekly is really getting about 288mg of testosterone into his body each week. This is clearly a great increase over the endogenous testosterone level of the average male, which is in the range of 2.5 to 11 mg per day. But the general point is that during a cycle of Testosterone suspension we will often see a much more dramatic intake of testosterone on average than is typically utilized with oils. Following common advice, the athlete will commonly inject a full 100mg of testosterone daily, a total of 700 milligrams per week. This is up to 40 times the amount produced by a normal male. Those who have attempted such a cycle are rarely disappointed with the results, as such heavy doses of this hormone will produce nothing less than a dramatic weight gain.
The most popular practice with Testosterone suspension is to inject the drug every day. The dosage will vary greatly depending on the needs of the individual, but is most often in the range of 50mg to 100mg per shot. In most cases the results will be amazing. Although some users will complain about discomfort when injecting water-based steroids, suspension is usually well tolerated.
As would be expected with a strong androgen, suspension can produce a number of unpleasant side effects. As with any testosterone product there will be a high rate of estrogen conversion. Estrogen levels in fact build very quickly with Testosterone suspension, which is probably the worst testosterone to use when wishing to avoid water bloat. Gynecomastia can also develop very quickly during a cycle, and in many cases this drug will be intolerable without additionally taking an anti-estrogen. A combination of Nolvadex and Proviron is an effective way to avoid experiencing such side effects, and is often taken from the onset of a cycle in order to prevent such occurrences before they become a problem. Sensitive individuals may find an investment in the anti-aromatase Arimidex, Femara, or Aromasin to be wiser. These anti-aromatase drugs are much more effective at controlling estrogen. It is also important that the athlete monitor blood pressure and kidney functions closely during a heavy cycle, as water retention becomes more pronounced. Although testosterone puts very little strain on the liver, this drug can be harsh to the kidneys at higher dosages. Of course if the athlete is encountering noticeably high blood pressure or trouble urinating (pain or darkening of the urine), the cycle should probably be discontinued and the doctor paid a visit. Since it converts to DHT. one can therefore expect to endure oily skin, acne, increased aggression and body/facial hair growth during a typical cycle. Propecia/Proscar would be a good idea for those predisposed to male pattern baldness, as suspension is known to aggravate this condition quite easily. Men with an existing hair loss problem may actually prefer to stay far away from this steroid altogether, finding it to be just to strong an item to take risks with. The slower acting oil based injectables like enanthate or cypionate would be a much better place to start with if one still desires to use an injectable testosterone.
Endogenous testosterone production will be quickly and efficiently reduced when using suspension. This can often reach the point of severe testicular shrinkage (atrophy). Some athletes will periodically take HCG while on a cycle, in order to keep this effect to a minimum. Even if no such drug is used during, a combination of HCG and Clornid/Nolvadex should always be used as the cycle is discontinued.
Overall, suspension is an extremely powerful drug, but also one that is prone to causing many side effects. Those looking for only a potent mass agent need not look no further, Suspension will certainly get the job done.


.........charley

 

[nick52]

great info charlie thank you!

suspension or test suspended in water when injected is definetely an eye opener, not for the faint of heart,


but how bad do you want to grow, me whatever it takes, pain is just another feeling it goes away

 

[Calves of Steel]

How can trenbolone be liver toxic and yet testosterone is not? It has no side-groups that testosterone doesn't have. Just one less methyl group (like nandrolone) and a bunch of double bonds. It's metabolized into glucuronides and sulfides the same way that most other drugs or phytochemicals are. From the look of it, it has to either be one of the esters that are commonly attached to it, or the solution its in, not the drug itself.

<Tren

<Test

 

[btex34n88]

see that little black line missing on the left side of the tren? TOXIC......honestly not sure, am curious to find out tho.