Calling all hgh experts

[VictorZ06]

how about dicks? does it make your dick bigger?

All kidding aside, but I did notice more girth a few months after I started, it was my wife who pointed it out to me. Nothing drastic, but def noticeable. Not far fetched seeing how GH is known to make most of your internal organs grow.



/V

 

[banker23]

I fully agree with Heavy and GMO, like I said in my post...both test (yes, and tren) can cause hyperplasia. Not at the same rate as GH though. Taking them together multiplies the effect. And the strongest anabolic hormone is insulin, not HGH. IMHO. Good posts guys.



/V

Victor, I am doing an internet seach on insulin as an anabolic and all I am finding is pretty negatively and possibly biased against the idea. Do you have any links to any information that covers proper use and risk mitigation? Thanks.

 

[VictorZ06]

i had a question since we are on the topic of GH, victor mentioned that his feet grew one size and his wrist as well, does HGH change features on the face as well? does it make your face bigger?

Thankfully no, not in my case...but yes in others.

The lips, nose, tongue, jaw and forehead increase in size and the fingers and toes widen and become spade-like. The organs and digestive system may also increase in size, which may eventually cause heart failure....but this is caused from using extremely high doses for extended periods of time. A condition called gigantism.

Though it's said to happen usually before puberty, it can happen if you use to much HGH. Some dumb asses have used this shit at 30-50iu a day.....stupid. Some have all the money in the world and because they don't see drastic changes like we do with AAS, they up their dose extremely high thinking it will do them good. Not.



/V

 

[poohiron]

I read all of the posts and when we talk of hyperplasia we generally mean myofiber hyperplasia. Hyperplasia can refer to sarcoplasmic, mitochondrial, myofibrillar, etc. But just because there is evidence linking test to satellite cell hyperplasia only means that progenitor cell hyperplasia has occurred. Without differentiation the point is moot.
I suppose this is just a clarification because I subscribe to most of the views represented. I have read a shitload of conflicting research. Some of the positive research from Yamada, Antonio, Gonyea, etc. makes alot of sense in light of practical application.

 

[VictorZ06]

Victor, I am doing an internet seach on insulin as an anabolic and all I am finding is pretty negatively and possibly biased against the idea. Do you have any links to any information that covers proper use and risk mitigation? Thanks.

There are so many studies out there, but I'll try to find the best one that addresses your question. I can tell you that slin is frown upon for many reasons due to it's possible misuse that can ultimately lead to death. I picked it up because I reached my genetic potential, and thought about going pro many years back. Insulin is used as a "transport" or a bus if you will, that shuttles all nutrients throughout your body...including HGH. That's why I said I use a different dosing protocol when I toss slin into the mix.




/V

(I mentioned this in another thread, but because of it's dangers....I really don't like to dish out advice on insulin, because of all it's possible dangerous repercussions.)

 

[banker23]

All kidding aside, but I did notice more girth a few months after I started, it was my wife who pointed it out to me. Nothing drastic, but def noticeable. Not far fetched seeing how GH is known to make most of your internal organs grow.



/V

I will immediately commence a 24 hour iv drip of GH right into my dick.

I want people to nickname me tripod! I'll cancel my gym membership and just squat my dick from now on!

Thanks VicZ06!

 

[GMO]

Taking them together multiplies the effect. And the strongest anabolic hormone is insulin, not HGH. IMHO. Good posts guys.



/V

This^^^

Nothing beats a slin/GH/AAS cycle...period.

 

[banker23]

There are so many studies out there, but I'll try to find the best one that addresses your question. I can tell you that slin is frown upon for many reasons due to it's possible misuse that can ultimately lead to death. I picked it up because I reached my genetic potential, and thought about going pro many years back. Insulin is used as a "transport" or a bus if you will, that shuttles all nutrients throughout your body...including HGH. That's why I said I use a different dosing protocol when I toss slin into the mix.




/V

(I mentioned this in another thread, but because of it's dangers....I really don't like to dish out advice on insulin, because of all it's possible dangerous repercussions.)

in other words, I will probably never get to the point that I need it (genetic max). I'm not ever going to compete, I am just trying to reach more mass and then lean back out to about 15% (abs visible but not dry looking) which is where I think I look and feel my best.

p.s. I am still interested in reading up on it though if anyone can post some links (not the negative ones, I already found plenty of those).

 

[~RaZr~]

in other words, I will probably never get to the point that I need it (genetic max). I'm not ever going to compete, I am just trying to reach more mass and then lean back out to about 15% (abs visible but not dry looking) which is where I think I look and feel my best.

Banker23
IMHO, slin is really a dangerous drug if you do not know what you are doing. I am not telling you what to do, but from my own experience with diabetic patients and the literature that I have read, I would really consider this choice as a last resort.

 

[banker23]

There are so many studies out there, but I'll try to find the best one that addresses your question. I can tell you that slin is frown upon for many reasons due to it's possible misuse that can ultimately lead to death. I picked it up because I reached my genetic potential, and thought about going pro many years back. Insulin is used as a "transport" or a bus if you will, that shuttles all nutrients throughout your body...including HGH. That's why I said I use a different dosing protocol when I toss slin into the mix.




/V

(I mentioned this in another thread, but because of it's dangers....I really don't like to dish out advice on insulin, because of all it's possible dangerous repercussions.)

Is Insulin and IGF-1 the same thing?

 

[GMO]

Banker23
IMHO, slin is really a dangerous drug if you do not know what you are doing. I am not telling you what to do, but from my own experience with diabetic patients and the literature that I have read, I would really consider this choice as a last resort.

^^^I agree 100%.

AAS, GH use and genetic limits should be reached before employing slin...and even then, you should have a vet walk you through it.

 

[banker23]

Banker23
IMHO, slin is really a dangerous drug if you do not know what you are doing. I am not telling you what to do, but from my own experience with diabetic patients and the literature that I have read, I would really consider this choice as a last resort.

Thanks, I am not even considering this right now but I do want to learn about it at least. Don't want to waste anyone's time in here but I don't want to be ignorant on this subject either. I'll shut up now before it looks like I'm thread-jacking. Sorry OP.

 

[~RaZr~]

Is Insulin and IGF-1 the same thing?

Yes and no. Quoted from IGF1.net

IGF-1 is a hormone that is produced when the liver is stimulated by human growth hormone. When levels of HGH rise in the blood, the liver responds by producing more IGF-1. These higher "bursts" spur growth and regeneration by the body's cells, especially in muscle cells. Increases in IGF-1 levels have shown positive effects on increases in muscle strength, size, and efficiency. When you do not have enough IGF-1 in your body, whether caused by disease, malnutrition or a hormone imbalance, your growth can be stunted.

The primary purpose of IGF-1 is to stimulate cell growth. Every cell in the human body can be affected by IGF-1, but cells in muscle, cartilage, bone, liver, kidney, skin tissue, lungs, and nerves tend to be most positively affected.

Thanks, I am not even considering this right now but I do want to learn about it at least. Don't want to waste anyone's time in here but I don't want to be ignorant on this subject either. I'll shut up now before it looks like I'm thread-jacking. Sorry OP.

It's all good brother. Knowledge is power...

 

[VictorZ06]

Is Insulin and IGF-1 the same thing?

No. Look at slin as the delivery system.



/V

 

[heavyiron]

I finished a short article on HGH today if you guys want some practical application.

http://www.ironmagazineforums.com/unclez/147565-human-growth-hormone-practical-application.html

 

[VictorZ06]

in other words, I will probably never get to the point that I need it (genetic max). I'm not ever going to compete, I am just trying to reach more mass and then lean back out to about 15% (abs visible but not dry looking) which is where I think I look and feel my best.

Bro, if you have not reached your genetic potential (or come close to it), I strongly advice against the use of it. The ONLY reason why I started using it is because I near reached my maximum potential and considered going pro many years back. If you are not going pro, I don't see the point in taking such risks. And as GMO pointed out, if one ever decides to go ahead and use it, a pro/vet should be by your side to walk you through all the science, step by step. It's also best to get advice from seasoned nutritional pros who have worked with body builders and slin in the past. There is no room for any error.



/V

 

[VictorZ06]

I finished a short article on HGH today if you guys want some practical application.

http://www.ironmagazineforums.com/unclez/147565-human-growth-hormone-practical-application.html

Well done bro! And as always, I love the pics!!!



/V

 

[heavyiron]

Testosterone-induced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men

Indrani Sinha-Hikim,1 Stephen M. Roth,2 Martin I. Lee,1 and Shalender Bhasin1

1Division of Endocrinology, Metabolism, and Molecular Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California 90059; and 2Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvamia 15261
Submitted 22 August 2002 ; accepted in final form 26 March 2003

ABSTRACT


Testosterone (T) supplementation in men induces muscle fiber hypertrophy. We hypothesized that T-induced increase in muscle fiber size is associated with a dose-dependent increase in satellite cell number. We quantitated satellite cell and myonuclear number by using direct counting and spatial orientation methods in biopsies of vastus lateralis obtained at baseline and after 20 wk of treatment with a gonadotropin-releasing hormone agonist and a 125-, 300-, or 600-mg weekly dose of T enanthate. T administration was associated with a significant increase in myonuclear number in men receiving 300- and 600-mg doses. The posttreatment percent satellite cell number, obtained by direct counting, differed significantly among the three groups (ANCOVA P < 0.000001); the mean posttreatment values (5.0 and 15.0%) in men treated with 300- and 600-mg doses were greater than baseline (2.5 and 2.5%, respectively, P < 0.05 vs. baseline). The absolute satellite cell number measured by spatial orientation at 20 wk (1.5 and 4.0/mm) was significantly greater than baseline (0.3 and 0.6/mm) in men receiving the 300- and 600-mg doses (P < 0.05). The change in percent satellite cell number correlated with changes in total (r = 0.548) and free T concentrations (r = 0.468). Satellite cell and mitochondrial areas were significantly higher and the nuclear-to-cytoplasmic ratio lower after treatment with 300- and 600-mg doses. We conclude that T-induced muscle fiber hypertrophy is associated with an increase in satellite cell number, a proportionate increase in myonuclear number, and changes in satellite cell ultrastructure.

 

[~RaZr~]

I finished a short article on HGH today if you guys want some practical application.

http://www.ironmagazineforums.com/unclez/147565-human-growth-hormone-practical-application.html

Damn Heavy you should be a professor!

 

[VictorZ06]

^He is in my book....even when drunk! lol




/V

 

[poohiron]

Testosterone-induced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men

Indrani Sinha-Hikim,1 Stephen M. Roth,2 Martin I. Lee,1 and Shalender Bhasin1

1Division of Endocrinology, Metabolism, and Molecular Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California 90059; and 2Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvamia 15261
Submitted 22 August 2002 ; accepted in final form 26 March 2003

ABSTRACT


Testosterone (T) supplementation in men induces muscle fiber hypertrophy. We hypothesized that T-induced increase in muscle fiber size is associated with a dose-dependent increase in satellite cell number. We quantitated satellite cell and myonuclear number by using direct counting and spatial orientation methods in biopsies of vastus lateralis obtained at baseline and after 20 wk of treatment with a gonadotropin-releasing hormone agonist and a 125-, 300-, or 600-mg weekly dose of T enanthate. T administration was associated with a significant increase in myonuclear number in men receiving 300- and 600-mg doses. The posttreatment percent satellite cell number, obtained by direct counting, differed significantly among the three groups (ANCOVA P < 0.000001); the mean posttreatment values (5.0 and 15.0%) in men treated with 300- and 600-mg doses were greater than baseline (2.5 and 2.5%, respectively, P < 0.05 vs. baseline). The absolute satellite cell number measured by spatial orientation at 20 wk (1.5 and 4.0/mm) was significantly greater than baseline (0.3 and 0.6/mm) in men receiving the 300- and 600-mg doses (P < 0.05). The change in percent satellite cell number correlated with changes in total (r = 0.548) and free T concentrations (r = 0.468). Satellite cell and mitochondrial areas were significantly higher and the nuclear-to-cytoplasmic ratio lower after treatment with 300- and 600-mg doses. We conclude that T-induced muscle fiber hypertrophy is associated with an increase in satellite cell number, a proportionate increase in myonuclear number, and changes in satellite cell ultrastructure.

Interesting research, heavy. So we see an association of progenitor cells to the degree of hypertrophy induced by testosterone. Just wonder if there were more specifics on differentiation of those progenitor cells. Correlation doesn't prove causation so we can induce what from this? Differentiation of the increased satellite cells caused the myofibullar hypertrophy? Good info...