So what if the half life is actually 11 days? I think after a few weeks of pinning once a week there's gonna be enough built up residual of hormone that will carry you through the week. I still think its pointless to pin twice a week but I understand your logic.
If the type of oil, the concentration and the muscle pinned never change, and you happen to know that in your body, pinned this way it is indeed 11 days - then once a week is great.
well the logic is that your blood levels dont drop as much. sure there is enough to carry you through the week ,but your levels are going to be on more of a roller coaster. i dont feel any different if i just pin once a week, but i do notice i get a little more acne if i do it just once a week, versus 2 or 3x a week..i dont have any bw to back it, but just sharing how my body responds
The extra acne is consistent with androgen levels being a little more elevated, briefly, with the less-frequent pinning.
I understand the logic but if the half life is longer than a week it doesnt matter much. My point Im making is who would want to pin twice a week when they probably wouldnt notice a difference.
If the halflife really were 11 days, as I mentioned above, you're golden. Thing is, it likely isn't, and pinning twice a week will keep you level regardless if the halflife is 5 days or 11.
I'll add that this may be a bigger deal for "true" hormone replacement therapy, where the object is to keep to normal physiologic blood levels. Pinning less frequently means a higher-than-normal spike if blood levels are to be maintained at least above the low level of normal before the next shot. For chronic administration, going that much too high for a few days every week may not be such a great idea, particularly when bodyfat may be higher-than-desireable. Pinning a lower dose solves this problem, but leaves blood levels at below-normal for a few days before the next pin.
At supraphysiologic levels, you won't return to normal inside a week, so this may be less of a concern, although the difference between the peak and the valley are more exaggerated. Personally, I'd still prefer to see steadier blood levels, since this means blood levels never go as low as they would with infrequent pinning, and particularly because aromatase expression will be minimized.
My .02.
I am quite aware that guys have been getting huge on a single shot a week for a long time. Lots of stuff works; some stuff is just a little more optimal. Ultimately, it's a judgement call. I just like for people to be informed when they make their choices.
BTW, you can look at the graph on this article to see what I'm getting at:
Daily testosterone and gonadotropin levels are similar in azoospermic and nonazoospermic normal men administered weekly testosterone: implications for male contraceptive development -- Amory et al. 22 (6): 1053 -- Journal of Andrology
Figure 1 shows blood levels at different dosings of test enanthate pinned weekly, after 6 months of treatment. Normal range is given as (2.8???10) ng/ml.
300mg weekly gave blood levels ranging from a high of about 22ng/ml one day after the once-weekly injection, to about 12ng/ml on day 7, at the nadir.
For 100mg weekly, blood levels ranged between about 5ng/ml and about 11 ng/ml, remaining above-normal for about two days.
